Salman M Hyder Selected Research

Neoplasm Metastasis (Metastasis)

1/2022	Role of Reactivating Mutant p53 Protein in Suppressing Growth and Metastasis of Triple-Negative Breast Cancer.
1/2019	APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice.
1/2018	A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts.
1/2017	Natural and synthetic progestins enrich cancer stem cell-like cells in hormone-responsive human breast cancer cell populations in vitro.
1/2017	Cholesterol biosynthesis inhibitor RO 48-8071 reduces progesterone receptor expression and inhibits progestin-dependent stem cell-like cell growth in hormone-dependent human breast cancer cells.
1/2017	Luteolin inhibits lung metastasis, cell migration, and viability of triple-negative breast cancer cells.
9/2010	Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude mice.
2/2005	p53-dependent inhibition of progestin-induced VEGF expression in human breast cancer cells.

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Salman M Hyder Research Topics

Disease

38	Neoplasms (Cancer) 02/2022 - 07/2002
36	Breast Neoplasms (Breast Cancer) 02/2022 - 07/2002
8	Neoplasm Metastasis (Metastasis) 01/2022 - 02/2005
3	Triple Negative Breast Neoplasms 01/2022 - 01/2017
3	Carcinogenesis 02/2016 - 09/2010
3	Breast Diseases (Breast Disease) 08/2012 - 10/2007
2	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2016
1	Ovarian Epithelial Carcinoma 01/2023
1	Ovarian Neoplasms (Ovarian Cancer) 01/2023
1	Hyperplasia 08/2011
1	Ischemia 01/2011
1	Lymphatic Metastasis 09/2010

Drug/Important Bio-Agent (IBA)

25	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 07/2002
25	Progestins (Progestagens)IBA 01/2017 - 07/2002
22	Estrogens (Estrogen)FDA Link 01/2019 - 04/2004
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2005
15	Hormones (Hormone)IBA 02/2022 - 09/2006
15	Progesterone CongenersIBA 01/2017 - 02/2005
12	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 01/2017 - 10/2007
10	Progesterone Receptors (Progesterone Receptor)IBA 01/2019 - 02/2005
7	Estrogen ReceptorsIBA 02/2022 - 04/2004
6	EnzymesIBA 01/2023 - 07/2014
6	Ro 48-8071IBA 01/2023 - 04/2011
6	CholesterolIBA 01/2023 - 07/2014
6	2,2- bis(hydroxymethyl)- 1- azabicyclo(2,2,2,)octan- 3- oneIBA 04/2011 - 10/2007
5	LigandsIBA 02/2022 - 02/2005
5	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2015 - 05/2008
5	Fulvestrant (Faslodex)FDA Link 09/2009 - 07/2002
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2006 - 07/2002
4	lanosterol synthaseIBA 01/2023 - 07/2014
4	FumaratesIBA 01/2023 - 07/2014
4	Norethindrone (Norethisterone)FDA LinkGeneric 01/2017 - 09/2010
4	FlavonoidsIBA 01/2015 - 08/2011
4	Messenger RNA (mRNA)IBA 10/2014 - 02/2005
4	ApigeninIBA 01/2013 - 09/2010
4	Progesterone FDA LinkGeneric 09/2010 - 07/2002
3	LuteolinIBA 01/2017 - 01/2015
3	SteroidsIBA 01/2016 - 09/2006
3	9,10-Dimethyl-1,2-benzanthraceneIBA 01/2013 - 09/2010
3	Estradiol (Delestrogen)FDA LinkGeneric 09/2010 - 04/2004
3	Mifepristone (RU 486)FDA Link 09/2010 - 07/2006
3	anthraceneIBA 01/2010 - 07/2006
3	Thrombospondin 1IBA 09/2009 - 04/2004
2	lissamine rhodamine B (sulforhodamine B)IBA 02/2022 - 07/2014
2	Estrogen Receptor betaIBA 02/2022 - 10/2007
2	eprenetapoptIBA 01/2019 - 01/2018
2	PhosphatidylserinesIBA 01/2019 - 01/2018
2	Aldehyde DehydrogenaseIBA 01/2017 - 01/2015
2	Norgestrel (DL-Norgestrel)FDA LinkGeneric 09/2010 - 09/2010
2	CurcuminIBA 01/2010 - 05/2008
2	Conditioned Culture MediaIBA 09/2009 - 08/2005
2	Angiogenesis InhibitorsIBA 10/2007 - 07/2006
2	progesterone receptor BIBA 12/2005 - 03/2004
2	Tamoxifen FDA LinkGeneric 12/2005 - 03/2004
1	liquiritigeninIBA 02/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2019
1	Tumor Suppressor Protein p53IBA 01/2018
1	Androgen Receptors (Androgen Receptor)IBA 01/2016
1	ImmunosorbentsIBA 01/2015
1	AndrogensIBA 10/2014
1	Fluvastatin FDA Link 07/2014
1	Simvastatin (Zocor)FDA LinkGeneric 07/2014
1	Antineoplastic Agents (Antineoplastics)IBA 01/2013
1	3- (5'- hydroxymethyl- 2'- furyl)- 1- benzylindazoleIBA 01/2013
1	Phytoestrogens (Phytoestrogen)IBA 01/2013
1	RANK LigandIBA 08/2012
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2012
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2012
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 12/2011
1	Small Interfering RNA (siRNA)IBA 12/2011
1	Complement System Proteins (Complement)IBA 12/2011
1	Adenosine Triphosphate (ATP)IBA 12/2011
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 08/2011
1	Monoclonal AntibodiesIBA 01/2011
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2011
1	Therapeutic UsesIBA 01/2011
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 09/2010
1	Megestrol Acetate (Borea)FDA LinkGeneric 09/2010
1	flavoneIBA 09/2010
1	turmeric extractIBA 01/2010
1	Extracellular Matrix ProteinsIBA 09/2009
1	Cysteine (L-Cysteine)FDA Link 03/2009
1	Angiogenic ProteinsIBA 03/2009
1	PolyphenolsIBA 05/2008
1	matrigelIBA 10/2007
1	Estrogen Receptor alphaIBA 10/2007
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 08/2005
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 02/2005
1	Transcription Factors (Transcription Factor)IBA 02/2005
1	Estrogen Receptor Modulators (Antiestrogen)IBA 07/2002

Therapy/Procedure

21	Therapeutics 02/2022 - 03/2004
9	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2017 - 08/2005
3	Contraception (Birth Control) 09/2010 - 08/2005
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2016
2	Aftercare (After-Treatment) 02/2016 - 01/2011
1	Castration 01/2016
1	Injections 09/2010
1	Estrogen Replacement Therapy 10/2007